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APOBEC2 Polyclonal Antibody, APC Conjugated

Product Specifications

Background

APOBEC2 is a 224 amino acid protein that belongs to the cytidine and deoxycytidylate deaminase family. Expressed exclusively in heart and skeletal muscle, APOBEC2 is thought to be a probable C (cytidine) to U (uridine) editing enzyme. However, unlike other members of the family, such as APOBEC1, which mediates the editing of apolipoprotein (apo) B mRNA, APOBEC2 does not display any detectable apoB mRNA editing activity. Also, APOBEC2 has been shown to have low, but definite, intrinsic cytidine deaminase activity.

Synonyms

Apolipoprotein B mRNA editing enzyme catalytic polypeptide 2; Apolipoprotein B mRNA editing enzyme catalytic polypeptide like 2; ARCD1; ARP1; MGC128604; ABEC2_HUMAN.

Gene ID

10930

Cellular Locus

Cytoplasm

Host

Rabbit

Immunogen

121-224/224

Target

APOBEC2

Clonality

Polyclonal

Isotype

IgG

Conjugation

APC

Source

KLH conjugated synthetic peptide derived from human APOBEC2

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

650nm/660nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

10930

Predicted Cross Reactivity

Human, Mouse, Rat

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