Phospho-APC6 (Thr560) Polyclonal Antibody, Cy5 Conjugated

Product Specifications

Background

Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.

Synonyms

Cell division cycle protein 16 homolog; Anaphase-promoting complex subunit 6; APC6; CDC16 homolog; CDC16Hs; Cyclosome subunit 6; CDC16; ANAPC6

Gene ID

8881

Modification Site

Ser560

Cellular Locus

Cytoplasm

Host

Rabbit

Target

Phospho-APC6 (Thr560)

Clonality

Polyclonal

Isotype

IgG

Conjugation

Cy5

Source

KLH conjugated synthetic phosphopeptide derived from human APC6 around the phosphorylation site of Ser560

Applications

IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

625,650nm/670nm

Concentration

1µg/µl

Dilution

IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

8881

Predicted Cross Reactivity

Human, Mouse, Rat, Dog, Cow, Sheep, Pig

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

E53A07587 50 µg

Recombinant Mouse CD55 / DAF Protein (His tag)

Ask

View Details

430236-01 100 mg

4-Amino-3-methoxyphenol

Ask

View Details

430236-02 250 mg

4-Amino-3-methoxyphenol

Ask

View Details

A69431-50UG 50 µg

RASSF4 Antibody, FITC conjugated

Ask

View Details

PVT84542 2 µg

PLV3-CMV-Casp7-3xFLAG-CopGFP-Puro Plasmid

Ask

View Details