MGluR5 Polyclonal Antibody, APC-Cy7 Conjugated

Product Specifications

Background

G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. Plays an important role in the regulation of synaptic plasticity and the modulation of the neural network activity (By similarity) .

Synonyms

Glu5R; Gprc1e; mGluR5; mGluR5b; AI850523; 6430542K11Rik; Metabotropic glutamate receptor 5; Grm5

Gene ID

108071

Swiss Prot

Q3UVX5

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Rat

Immunogen

201-300/1204

Target

MGluR5

Clonality

Polyclonal

Isotype

IgG

Conjugation

APC-Cy7

Source

KLH conjugated synthetic peptide derived from mouse GRM5

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

650nm/780nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

108071

Predicted Cross Reactivity

Human, Mouse, Dog, Sheep, Chicken

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