MGluR5 Polyclonal Antibody
Product Specifications
Background
G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. Plays an important role in the regulation of synaptic plasticity and the modulation of the neural network activity (By similarity) .
Synonyms
Glu5R; Gprc1e; mGluR5; mGluR5b; AI850523; 6430542K11Rik; Metabotropic glutamate receptor 5; Grm5
Gene ID
108071
Swiss Prot
Q3UVX5
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Rat
Immunogen
201-300/1204
Target
MGluR5
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from mouse GRM5
Applications
WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
108071
Predicted Cross Reactivity
Human, Mouse, Dog, Sheep, Chicken
Available Sizes
Curated Selection
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