ABCF2 Polyclonal Antibody, AbBy Fluor™ 405 Conjugated
Product Specifications
Background
ATP-binding cassette (ABC) transporters are an evolutionarily conserved family of widely-expressed proteins that use ATP hydrolysis to catalyze the transport of various molecules across extracellular and intracellular membranes. As the largest family of transmembrane proteins, ABC genes comprise several subfamilies. Eukaryotic ABC transporters are largely responsible for trafficking hydrophobic compounds either within the cell, as part of a metabolic process, or outside the cell, for transport to other organs or for secretion from the body. ABCF2 in particular plays a putative role in tumor suppression at metastatic sites and in the endocrine pathway for breast cancer and may be a prognostic marker for clear cell ovarian adenocarcinoma.
Synonyms
0710005O05Rik; ABC28; ABCF 2; ATP binding cassette sub family F GCN20 member 2; DKFZp586K1823; Drr3; E430001O06; EST133090; fb04f06; fc74f03; fd58d07; HUSSY 18; MABC1; MGC128735; ABCF2_HUMAN.
Gene ID
10061
Cellular Locus
Cytoplasm, Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Immunogen
301-400/623
Target
ABCF2
Clonality
Polyclonal
Isotype
IgG
Conjugation
AbBy Fluor™ 405
Source
KLH conjugated synthetic peptide derived from human ABCF2
Applications
IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
401nm/421nm
Concentration
1µg/µl
Dilution
IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
10061
Predicted Cross Reactivity
Pig
Curated Selection
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