DOCK2 Polyclonal Antibody, APC-Cy5.5 Conjugated
Product Specifications
Background
Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. Activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. May also participate in IL2 transcriptional activation via the activation of RAC2.
Synonyms
Dedicator of cytokinesis protein 2; DOCK2; KIAA0209
Gene ID
1794
Swiss Prot
Q92608
Cellular Locus
Cell membrane
Host
Rabbit
Immunogen
451-550/1830
Target
DOCK2
Clonality
Polyclonal
Isotype
IgG
Conjugation
APC-Cy5.5
Source
KLH conjugated synthetic peptide derived from human DOCK2
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
650nm/694nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
1794
Predicted Cross Reactivity
Human, Mouse, Rat, Dog, Cow, Sheep
Curated Selection
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