MAML3 Polyclonal Antibody, PE Conjugated
Product Specifications
Background
The three MAML genes are widely expressed in adult tissues but exhibit distinct expression patterns in mouse early spinal cord development. All MAML proteins localize to nuclear bodies, share a conserved basic domain in their N termini that binds to the ankyrin repeat domain of Notch, and contain a transcriptional activation domain in their C termini. MAML3 acts as a transcriptional coactivator for NOTCH proteins and has been shown to amplify NOTCH-induced transcription of HES1.
Synonyms
AV234550; BC049812; CAGH3; ERDA3; GDN; KIAA1816; MAM 2; MAM2; mastermind like 3 Drosophila; MGC59565; mKIAA1816; TNRC3; MAML3_HUMAN.
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Human
Immunogen
931-1030/1134
Target
MAML3
Clonality
Polyclonal
Isotype
IgG
Conjugation
PE
Source
KLH conjugated synthetic peptide derived from human MAML3
Applications
IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
496,564nm/578nm
Concentration
1µg/µl
Dilution
IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Predicted Cross Reactivity
Mouse, Rat, Cow, Sheep, Pig, Horse
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