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Kindlin 2 Polyclonal Antibody, PE-Cy5 Conjugated

Product Specifications

Background

Mig-2 recruits migfilin to cell-matrix adhesions, while the interaction with filamin mediates the association of migfilin with actin filaments. Together, Mig-2, migfilin and filamin define a connection between cell matrix adhesions and the actin cytoskeleton and participate in the orchestration of actin assembly and cell shape modulation. Mig-2 expression is transcriptionally elevated in leiomyomas and could be involved in its hormone-mediated growth of leiomyomas of the uterus. Expression of Mig-2 is ubiquitous, and it is found in numerous tumor tissues.

Synonyms

FLJ34213; FLJ44462; UNC112; FERM2_HUMAN; Fermitin family homolog 2; Fermt2; KIND2; Kindlin-2; MIG-2; MIG2; Mitogen-inducible gene 2 protein; PH domain-containing family C member 1; Pleckstrin homology domain containing family C with FERM domain member 1; Pleckstrin homology domain-containing family C member 1; PLEKHC1; UNC112B.

Gene ID

10979

Cellular Locus

Cytoplasm, Cell membrane

Host

Rabbit

Cross Reactivity

Human

Immunogen

352-420/680

Target

Kindlin 2

Clonality

Polyclonal

Isotype

IgG

Conjugation

PE-Cy5

Source

KLH conjugated synthetic peptide derived from human Kindlin 2/MIG2

Applications

WB

Purification

Purified by Protein A.

Excitation Emission

488nm/670nm

Concentration

1µg/µl

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

10979

Predicted Cross Reactivity

Mouse, Rat, Dog, Cow, Sheep, Pig, Horse, Chicken

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