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THEMIS Polyclonal Antibody, AbBy Fluor™ 488 Conjugated

Product Specifications

Background

Plays a central role in late thymocyte development by controlling both positive and negative T-cell selection. Required to sustain and/or integrate signals required for proper lineage commitment and maturation of T-cells. Regulates T-cell development through T-cell antigen receptor (TCR) signaling and in particular through the regulation of calcium influx and phosphorylation of Erk (By similarity) .

Synonyms

GASP; SPOT; TSEPA; C6orf190; C6orf207; bA325O24.3; bA325O24.4; Protein THEMIS; Thymocyte-expressed molecule involved in selection; THEMIS

Gene ID

387357

Swiss Prot

Q8N1K5

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Human

Immunogen

301-400/641

Target

THEMIS

Clonality

Polyclonal

Isotype

IgG

Conjugation

AbBy Fluor™ 488

Source

KLH conjugated synthetic peptide derived from human THEMIS

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

499nm/519nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

387357

Predicted Cross Reactivity

Mouse, Rat, Dog, Pig, Horse, Rabbit

Curated Selection

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