THEMIS Polyclonal Antibody, APC Conjugated
Product Specifications
Background
Plays a central role in late thymocyte development by controlling both positive and negative T-cell selection. Required to sustain and/or integrate signals required for proper lineage commitment and maturation of T-cells. Regulates T-cell development through T-cell antigen receptor (TCR) signaling and in particular through the regulation of calcium influx and phosphorylation of Erk (By similarity) .
Synonyms
GASP; SPOT; TSEPA; C6orf190; C6orf207; bA325O24.3; bA325O24.4; Protein THEMIS; Thymocyte-expressed molecule involved in selection; THEMIS
Gene ID
387357
Swiss Prot
Q8N1K5
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Cross Reactivity
Human
Immunogen
301-400/641
Target
THEMIS
Clonality
Polyclonal
Isotype
IgG
Conjugation
APC
Source
KLH conjugated synthetic peptide derived from human THEMIS
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
650nm/660nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
387357
Predicted Cross Reactivity
Mouse, Rat, Dog, Pig, Horse, Rabbit
Curated Selection
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