MSY2 Polyclonal Antibody, Cy5.5 Conjugated

MSY2 and YB-2 (MSY3,4) belong to the Y-box family of multifunctional proteins that regulate both transcription and translation (13) . Y-box proteins interact with a wide variety of nucleic acid structures to act as transcription factors and mRNA masking proteins (1) . The modular structure of Y-box proteins includes a highly conserved N-terminal cold-shock domain (CSD, equivalent to the bacterial cold-shock proteins) and four basic C-terminal domains containing arginine clusters and aromatic residues (4) . MSY2 is expressed in testis and ovary where it may repress translation of parental mRNA (5,6) . The gene encoding human MSY2 maps to chromosome 17p11.2-13.1 (5) . YB-2 (MSY3,4 in mouse) is also known as DNA binding protein A and is highly expressed in the testis, heart and muscle (7,8) . MSY2 and YB-2 bind to the consensus sequence 5'-UCCAUCA-3' contained in the Y-box element (9) .

Contrin; CSDA 3; CSDA3; DBPC; DNA binding protein C; DNA-binding protein C; FRGY2 homolog; Germ cell specic Y box binding protein; Germ cell-specic Y-box-binding protein; MGC118270; MGC45104; MSY 2; MSY2; MSY2 homolog; OTTMUSP00000006276; RGD1305068; Y box binding protein 2; Y-box-binding protein 2; YBOX2_HUMAN; YBX 2; YBX2.