N-Acetyl-D-galactosamine, 98%

N-Acetyl-D-galactosamine (GalNAc) is a terminal essential amino sugar derived from galactose and forms the antigens of blood group A in humans. N-Acetyl-D-galactosamine (GalNAc) interact with Soya bean agglutinin (SBA), hence decreasing the effects of SBA on cellular membrane permeability and tight junction protein expression in piglets[1]. N-Acetyl-D-galactosamine (GalNAc) inhibits the hemagglutinating activity by the lectin[2].

Product Specifications

CAS Number

[14215-68-0]

UNSPSC

12352200

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite; Galectin

Type

Biochemical Assay Reagents

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/n-acetyl-d-galactosamine.html

Purity

99.85

Solubility

H2O : 125 mg/mL (ultrasonic)

Smiles

CC(N[C@@H]1[C@H]([C@H]([C@H](O[C@@H]1O)CO)O)O)=O

Molecular Formula

C8H15NO6

Molecular Weight

221.21

Precautions

H302, H315, H319, H335

References & Citations

[1]Zhao B, et al. N-Acetyl-d-galactosamine prevents soya bean agglutinin-induced intestinal barrier dysfunction in intestinal porcine epithelial cells. J Anim Physiol Anim Nutr (Berl) . 2019 Jul;103 (4) :1198-1206.|[2]Sadanandan R, et al. Isolation, Purification and Characterisation of a D-galactose and N-acetyl-D-galactosamineSpecific Lectin from Marine Sponge Fasciospongia cavernosa. Protein Pept Lett. 2018;25 (9) :871-877.