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ZNF81 Polyclonal Antibody, AbBy Fluor™ 405 Conjugated

Product Specifications

Background

Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Kr_ppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF81, also known as HFZ20 or MRX45, is a transcriptional regulator belonging to the Kr_ppel C2H2-type zinc-finger protein family. It localizes to the nucleus and contains 12 C2H2-type zinc fingers and 1 KRAB domain. Mutations in the gene encoding ZNF81 are implicated in nonsyndromic X-linked mental retardation (XLMR) .

Synonyms

HFZ20; Zinc finger protein 81; ZNF81; ZNF81_HUMAN.

Gene ID

347344

Cellular Locus

Nucleus

Host

Rabbit

Immunogen

601-661/661

Target

ZNF81

Clonality

Polyclonal

Isotype

IgG

Conjugation

AbBy Fluor™ 405

Source

KLH conjugated synthetic peptide derived from human ZNF81

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

401nm/421nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

347344

Predicted Cross Reactivity

Human, Dog, Cow, Sheep, Pig, Horse, Chicken

Curated Selection

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