PNCK Polyclonal Antibody, Cy7 Conjugated
Product Specifications
Background
The Ca2+/calmodulin-dependent protein kinases (CaMKs) comprise a structurally related subfamily of serine/threonine kinases. CaMKI Beta (Ca2+/calmodulin-dependent protein kinase type 1B), also known as PNCK (pregnancy up-regulated non-ubiquitously expressed CaM kinase) or BSTK3, is a 343 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one protein kinase domain. Existing as multiple alternatively spliced isoforms, CaMKI Beta functions to catalyze the ATP-dependent phosphorylation of CaMKI, an event that activates CaMKI activity and may be important for Ca2+-triggered signaling cascades within the cell. The gene encoding CaMKI Beta maps to human chromosome X, which contains nearly 153 million base pairs and houses over 1,000 genes.
Synonyms
Calcium/calmodulin dependent protein kinase type 1B; Calcium/calmodulin-dependent protein kinase type 1B; CaM KI beta; CaM kinase I beta; CaM kinase IB; CaM-KI beta; CaMK1b; CaMKI beta; CaMKI-beta; EC 2.7.11.17; KCC1B_HUMAN; MGC45419; PNCK; Pregnancy up regulated non ubiquitously expressed CaM kinase; Pregnancy up-regulated non-ubiquitously-expressed CaM kinase.
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Immunogen
31-160/343
Target
PNCK
Clonality
Polyclonal
Isotype
IgG
Conjugation
Cy7
Source
KLH conjugated synthetic peptide derived from human PNCK
Applications
IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
743nm/767nm
Concentration
1µg/µl
Dilution
IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.biossantibodies.com/datasheets/bs-12134R-Cy7
Predicted Cross Reactivity
Human, Mouse, Rat, Cow, Sheep, Pig
Curated Selection
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