ACCN5 Polyclonal Antibody
Product Specifications
Background
ACCN5 is a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. DEG/ENaC superfamily members are amiloride-sensitive sodium channels that contain intracellular N- and C-termini, two hydrophobic transmembrane regions and a cysteine-containing extracellular loop. Localizing to the cell membrane, ACCN5 is a multi-pass membrane protein that is expressed in small intestine, jejunum and duodenum. ACCN5 is also expressed at low levels in rectum and testis. Existing as a homo- or heterotetramer, ACCN5 functions as a Na+-selective cation channel that, characteristic of its family, can be inhibited by amiloride.
Synonyms
Amiloride sensitive cation channel 5, intestinal; Amiloride sensitive sodium channel; intestine Na+ channel; amiloride-sensitive cation channel 5; HINAC; INAC; ASIC5_HUMAN.
Cellular Locus
Cell membrane
Host
Rabbit
Immunogen
231-350/505
Target
ACCN5
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human ACCN5
Applications
ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Predicted Cross Reactivity
Human, Mouse, Rat, Dog, Horse
Curated Selection
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