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P2RX7 Polyclonal Antibody, AbBy Fluor™ 647 Conjugated

Product Specifications

Background

Receptor for ATP that acts as a ligand-gated ion channel. Responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells.

Synonyms

P2X7; P2X purinoceptor 7; ATP receptor; P2Z receptor; Purinergic receptor; P2RX7

Gene ID

5027

Swiss Prot

Q99572

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Human

Immunogen

115-160/595

Target

P2RX7

Clonality

Polyclonal

Isotype

IgG

Conjugation

AbBy Fluor™ 647

Source

KLH conjugated synthetic peptide derived from human P2RX7

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

650nm/665nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

5027

Predicted Cross Reactivity

Mouse, Rat

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