P2RX7 Polyclonal Antibody, APC-Cy7 Conjugated
Product Specifications
Background
Receptor for ATP that acts as a ligand-gated ion channel. Responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells.
Synonyms
P2X7; P2X purinoceptor 7; ATP receptor; P2Z receptor; Purinergic receptor; P2RX7
Gene ID
5027
Swiss Prot
Q99572
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Human
Immunogen
115-160/595
Target
P2RX7
Clonality
Polyclonal
Isotype
IgG
Conjugation
APC-Cy7
Source
KLH conjugated synthetic peptide derived from human P2RX7
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
650nm/780nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
5027
Predicted Cross Reactivity
Mouse, Rat
Curated Selection
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