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5HT3A Receptor Polyclonal Antibody

Product Specifications

Background

This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses in neurons. It is a cation-specific, but otherwise relatively nonselective, ion channel.

Synonyms

HTR3; 5HT3R; 5-HT-3; 5-HT3A; 5-HT3R; 5-hydroxytryptamine receptor 3A; 5-HT3-A; 5-hydroxytryptamine receptor 3; Serotonin receptor 3A; Serotonin-gated ion channel receptor; HTR3A

Gene ID

3359

Swiss Prot

P46098

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Immunogen

31-130/478

Target

5HT3A Receptor

Clonality

Polyclonal

Isotype

IgG

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from human 5HT3A Receptor/SR-3A

Applications

ELISA, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

ELISA (1:500-1000), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Gene ID URL

3359

Predicted Cross Reactivity

Dog, Cow, Sheep, Pig, Horse

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