PAX8 Polyclonal Antibody, AbBy Fluor™ 594 Conjugated
Product Specifications
Background
This protein is a member of the paired box (PAX) family of transcription factors, typically containing a paired box domain, an octapeptide, and a paired-type homeodomain. This family plays critical roles during fetal development and cancer growth. The specific function of the PAX8 is unknown but it may involve kidney cell differentiation, thyroid development, or thyroid dysgenesis. Alternative splicing in the gene by inclusion or exclusion of exons 7 and/or 8 has produced several known products but the biological significance of the variants is unknown. Several other splice variants have been proposed but the full nature of these products has not been described. Pax8 is also a marker of otic progenitor cells.
Synonyms
Paired Box Gene 8; paired box homeotic gene 8; Paired box protein Pax 8; Paired Domain Gene 8; PAX 8; PAX-8
Gene ID
18510
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Human, Rat
Target
PAX8
Clonality
Polyclonal
Isotype
IgG
Conjugation
AbBy Fluor™ 594
Source
KLH conjugated synthetic peptide derived from mouse PAX8
Applications
WB, IF (IHC-P), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
590nm/617nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
18510
Predicted Cross Reactivity
Mouse, Dog, Cow
Curated Selection
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