GPR88 Polyclonal Antibody, HRP Conjugated
Product Specifications
Background
G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR88 (G protein-coupled receptor 88), also known as STRG, is a 384 amino acid multi-pass membrane protein that localizes to the cell membrane and belongs to the G protein coupled receptor family. Expressed exclusively in striatum, GPR88 functions as an orphan receptor that may be involved in signaling pathways throughout the cell. Human GPR88 shares 95% sequence identity with its rat counterpart, suggesting a conserved role between species.
Synonyms
G protein coupled receptor 88; G protein-coupled receptor 88; G-protein coupled receptor 88; Probable G protein coupled receptor 88; STRG; Striatum specic G protein coupled receptor; GPR88_HUMAN; GPCR88.
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Mouse, Rat
Immunogen
64-170/384
Target
GPR88
Clonality
Polyclonal
Isotype
IgG
Conjugation
HRP
Source
KLH conjugated synthetic peptide derived from human G protein coupled receptor 88
Applications
WB, ELISA, IHC-P, IHC-F
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Predicted Cross Reactivity
Human, Dog, Cow, Rabbit
Curated Selection
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