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GPR88 Polyclonal Antibody, AbBy Fluor™ 555 Conjugated

Product Specifications

Background

G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR88 (G protein-coupled receptor 88), also known as STRG, is a 384 amino acid multi-pass membrane protein that localizes to the cell membrane and belongs to the G protein coupled receptor family. Expressed exclusively in striatum, GPR88 functions as an orphan receptor that may be involved in signaling pathways throughout the cell. Human GPR88 shares 95% sequence identity with its rat counterpart, suggesting a conserved role between species.

Synonyms

G protein coupled receptor 88; G protein-coupled receptor 88; G-protein coupled receptor 88; Probable G protein coupled receptor 88; STRG; Striatum specic G protein coupled receptor; GPR88_HUMAN; GPCR88.

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Mouse, Rat

Immunogen

64-170/384

Target

GPR88

Clonality

Polyclonal

Isotype

IgG

Conjugation

AbBy Fluor™ 555

Source

KLH conjugated synthetic peptide derived from human G protein coupled receptor 88

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

553nm/568nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Predicted Cross Reactivity

Human, Dog, Cow, Rabbit

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