E3 ligase Ligand 7

E3 ligase Ligand 7 (Compound 6) is a ligand for E3 ligase. E3 ligase Ligand 7 can be utilized for the synthesis of PROTAC BET Degrader-12 (HY-158764) [1].

Product Specifications

CAS Number

[37630-54-9]

UNSPSC

12352005

Target

Ligands for E3 Ligase

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/e3-ligase-ligand-7.html

Smiles

O=C(O)/C(C#N)=C/C1=CC=C2C=CC=CC2=C1

Molecular Formula

C14H9NO2

Molecular Weight

223.23

References & Citations

[1]Tin G, et al., Discovery of a DCAF11-dependent cyanoacrylamide-containing covalent degrader of BET-proteins. Bioorg Med Chem Lett. 2024 Jul 15;107:129779.