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IL-23 Polyclonal Antibody

Product Specifications

Background

Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.

Synonyms

P19; SGRF; IL-23; IL-23A; IL23P19; Interleukin-23 subunit alpha; IL-23 subunit alpha; IL-23-A; Interleukin-23 subunit p19; IL-23p19; IL23A; UNQ2498/PRO5798

Gene ID

51561

Swiss Prot

Q9NPF7

Cellular Locus

Secreted

Host

Rabbit

Cross Reactivity

Human, Rat

Immunogen

101-196/196

Target

IL-23

Clonality

Polyclonal

Isotype

IgG

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from human Il23a

Applications

WB, ELISA, IHC-P, IHC-F, IF

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF ()

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Product Datasheet

https://www.biossantibodies.com/datasheets/bs-1193R

Gene ID URL

51561

Predicted Cross Reactivity

Mouse

Available Sizes

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