ITM2C Polyclonal Antibody
Product Specifications
Background
Negative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking its access to alpha-and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation.
Synonyms
BRI3; BRICD2C; BRICHOS domain containing 2C; Cerebral protein 14; CT-BRI3; E25; E25C ; Integral membrane protein 2C; Integral membrane protein 3; Itm2c; ITM2C_HUMAN; ITM3 antibodyNPD018; Transmembrane protein BRI3.
Gene ID
81618
Swiss Prot
Q9NQX7
Cellular Locus
Cytoplasm, Cell membrane
Host
Rabbit
Immunogen
3-88/267
Target
ITM2C
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human ITM2C
Applications
WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
81618
Predicted Cross Reactivity
Human, Mouse, Rat, Dog, Cow, Sheep, Pig, Horse
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
NB-E20138 96 Well
Mouse hepatitis B virus surface antibody, HBsAb ELISA Kit
Sign In for Pricing
View Details 
bsm-62848R-Cy5.5 100 µL
Phospho-Syk (Tyr323) Recombinant Antibody, Cy5.5 Conjugated
Sign In for Pricing
View Details 
abx375763 100 µg
Suppressor of Cytokine Signaling 7 (SOCS7) Antibody
Sign In for Pricing
View Details