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HES6 Polyclonal Antibody

Product Specifications

Background

Does not bind DNA itself but suppresses both HES1-mediated N box-dependent transcriptional repression and binding of HES1 to E box sequences. Also suppresses HES1-mediated inhibition of the heterodimer formed by ASCL1/MASH1 and TCF3/E47, allowing ASCL1 and TCF3 to up-regulate transcription in its presence. Promotes cell differentiation (By similarity) .

Synonyms

HES-6; bHLHb41; bHLHc23; C-HAIRY1; Transcription cofactor HES-6; Class B basic helix-loop-helix protein 41; Hairy and enhancer of split 6; HES6

Gene ID

55502

Swiss Prot

Q96HZ4

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human

Immunogen

1-80/224

Target

HES6

Clonality

Polyclonal

Isotype

IgG

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from human HES6

Applications

WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Gene ID URL

55502

Predicted Cross Reactivity

Mouse, Rat, Cow, Pig

Curated Selection

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