Tetanus Toxin heavy chain Antibody
Product Specifications
Background
Tetanus toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the '76-Gln-|-Phe-77' bond of synaptobrevin-2.
Synonyms
Tetanus toxin; Tentoxylysin; tetX; CTC_p60
Gene ID
24255210
Swiss Prot
P04958
Cellular Locus
Secreted
Host
Rabbit
Cross Reactivity
Bacteria
Immunogen
801-900/1315
Target
Tetanus Toxin heavy chain
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from Clostridium tetani E88 Tetanus toxin heavy chain
Applications
ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
24255210
Cross Reactivity Details
Clostridium tetani E88
Available Sizes
Curated Selection
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