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SRSF7 Polyclonal Antibody, AbBy Fluor™ 488 Conjugated

Product Specifications

Background

Required for pre-mRNA splicing. Can also modulate alternative splicing in vitro. Represses the splicing of MAPT/Tau exon 10. May function as export adapter involved in mRNA nuclear export such as of histone H2A. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NXF1 pathway) ; enhances NXF1-NXT1 RNA-binding activity. RNA-binding is semi-sequence specific.

Synonyms

9G8; AAG3; SFRS7; Serine/arginine-rich splicing factor 7; Splicing factor 9G8; Splicing factor, arginine/serine-rich 7; SRSF7

Gene ID

6432

Swiss Prot

Q16629

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Rat

Immunogen

2-70/238

Target

SRSF7

Clonality

Polyclonal

Isotype

IgG

Conjugation

AbBy Fluor™ 488

Source

KLH conjugated synthetic peptide derived from human SFRS7

Applications

IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

499nm/519nm

Concentration

1µg/µl

Dilution

IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

6432

Predicted Cross Reactivity

Human, Mouse, Cow, Chicken, Zebrafish

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