N-cadherin Polyclonal Antibody, PerCP-Cy5.5 Conjugated

Product Specifications

Background

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density (By similarity) .

Synonyms

CDHN; NCAD; CD325; CDw325; Cadherin-2; Neural cadherin; N-cadherin; CDH2; CADH2_HUMAN

Gene ID

1000

Swiss Prot

P19022

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Immunogen

701-800/905

Target

N-cadherin

Clonality

Polyclonal

Isotype

IgG

Conjugation

PerCP-Cy5.5

Source

KLH conjugated synthetic peptide derived from human N-cadherin

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

482nm/694nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

1000

Predicted Cross Reactivity

Cow, Sheep, Pig, Horse, Rabbit

Curated Selection

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