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NUP107 Polyclonal Antibody, FITC Conjugated

Product Specifications

Background

Nuclear pore complexes (NPCs) are the channels for the bi-directional movement of macromolecules between the nucleus and cytoplasm, and contain more than 100 different subunits. Many of them belong to a family called nucleoporins, which are characterized by the presence of O-linked N-acetylglucosamine moieties and a distinctive pentapeptide repeat (XFXFG) . Nuclear pore complex protein Nup107 (Nucleoporin Nup107) is an essential part of the nuclear pore complex which is composed of Nup133, Nup160, Nup107 and Nup96. Nup107 is active in assembling peripheral proteins into this complex. The protein, located on both the nuclear and cytoplasmic sides of the pore, is important in RNA export.

Synonyms

107 kDa nucleoporin; NPC proteins; NU107_HUMAN; Nuclear pore complex protein Nup107; Nucleoporin 107kDa; Nucleoporin Nup107; NUP 107; NUP 84; NUP107; NUP153; NUP155; NUP84; NUP98.

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human

Immunogen

501-600/925

Target

NUP107

Clonality

Polyclonal

Isotype

IgG

Conjugation

FITC

Source

KLH conjugated synthetic peptide derived from human Nuclear pore complex protein Nup107

Applications

WB, FCM

Purification

Purified by Protein A.

Excitation Emission

494nm/518nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), FCM (1:20-100)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Predicted Cross Reactivity

Mouse, Rat, Pig, Horse, Rabbit

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