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BLMH Polyclonal Antibody, AbBy Fluor™ 488 Conjugated

Product Specifications

Background

Bleomycin hydrolase (BMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution; however, the only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM), an essential component of combination chemotherapy regimens for cancer. The protein contains the signature active site residues of the cysteine protease papain superfamily. [provided by RefSeq, Jul 2008].

Synonyms

BH; bleomycin hydrolase; BLM hydrolase; BMH; EC 3.4.22.40; BLMH_HUMAN.

Cellular Locus

Cytoplasm

Host

Rabbit

Cross Reactivity

Mouse, Rat

Immunogen

308-400/455

Target

BLMH

Clonality

Polyclonal

Isotype

IgG

Conjugation

AbBy Fluor™ 488

Source

KLH conjugated synthetic peptide derived from human BLMH

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

499nm/519nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Predicted Cross Reactivity

Human, Dog, Cow, Sheep, Pig, Horse, Rabbit

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