Aph-1b Polyclonal Antibody, PerCP Conjugated

Product Specifications

Background

Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (beta-amyloid precursor protein) . It probably represents a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex. Probably present in a minority of gamma-secretase complexes compared to APH1A.

Synonyms

PSFL; APH-1B; PRO1328; TAAV688; Gamma-secretase subunit APH-1B; Aph-1beta; Presenilin-stabilization factor-like; APH1B; UNQ688/PRO1328

Gene ID

83464

Swiss Prot

Q8WW43

Cellular Locus

Cell membrane

Host

Rabbit

Immunogen

51-150/257

Target

Aph-1b

Clonality

Polyclonal

Isotype

IgG

Conjugation

PerCP

Source

KLH conjugated synthetic peptide derived from human Aph-1b

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

482nm/677nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

83464

Predicted Cross Reactivity

Human, Mouse, Rat, Dog, Cow, Sheep, Pig

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