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OR10A5 Polyclonal Antibody, FITC Conjugated

Product Specifications

Background

Olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response that leads to the perception of smell. While they share a seven transmembrane domain structure with many neurotransmitter and hormone receptors, olfactory receptors are responsible for the recognition and transduction of odorant signals. OR10A2 (olfactory receptor 10A2) and OR10A5 (olfactory receptor 10A5) are multi-pass membrane proteins that belong to the G-protein coupled receptor 1 family and are encoded by genes that map to human chromosome 11p15.4. Chromosome 11 houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that map to chromosome 11.

Synonyms

HP3; O10A5_HUMAN; Olfactory receptor 10A1; Olfactory receptor 10A5; Olfactory receptor 11-403; Olfactory receptor-like protein JCG6; OR10A1; OR10A5; OR11-403; R10A1.

Cellular Locus

Cell membrane

Host

Rabbit

Immunogen

231-317/317

Target

OR10A5

Clonality

Polyclonal

Isotype

IgG

Conjugation

FITC

Source

KLH conjugated synthetic peptide derived from human OR10A5

Applications

IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

494nm/518nm

Concentration

1µg/µl

Dilution

IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Predicted Cross Reactivity

Human, Mouse, Rat, Dog, Cow, Sheep, Horse, Rabbit

Curated Selection

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