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WBP2 Polyclonal Antibody, PE-Cy7 Conjugated

Product Specifications

Background

WW domain-binding protein 2 (WBP2) is a 261 amino acid protein expressed in most tissues. The WW domain is composed of 38 to 40 semi-conserved amino acids and is shared by various groups of proteins, including structural, regulatory and signaling proteins. The domain mediates protein-protein interactions through the binding of polyproline ligands. WBP2 binds to the WW domain of Yes-associated protein (YAP), WW domain containing E3 ubiquitin protein ligase 1 (AIP5) and WW domain containing E3 ubiquitin protein ligase 2 (AIP2) . The gene encoding WBP2 is located on human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes, some of which are involved in tumor suppression and in the pathogenesis of Li-Fraumeni syndrome, early onset breast cancer and a predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.

Synonyms

MGC18269; WBP 2; WBP-2; Wbp2; WBP2_HUMAN; WW domain binding protein 2; WW domain-binding protein 2.

Host

Rabbit

Cross Reactivity

Human

Immunogen

1-100/261

Target

WBP2

Clonality

Polyclonal

Isotype

IgG

Conjugation

PE-Cy7

Source

KLH conjugated synthetic peptide derived from human WBP2

Applications

WB

Purification

Purified by Protein A.

Excitation Emission

488nm/780nm

Concentration

1µg/µl

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Predicted Cross Reactivity

Mouse, Rat, Dog, Cow, Sheep, Pig, Horse

Curated Selection

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