Zic2 Polyclonal Antibody, APC-Cy7 Conjugated
Product Specifications
Background
Zic2 is a C2H2 zinc finger transcription factor that influences forebrain development. Zic2 is a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. Zic2 transcript is abundant in the dorsal neural tube/spinal cord, and in the hindbrain. A polyhistidine tract polymorphism in this gene may be associated with increased risk of neural tube defects. This gene is closely linked to a gene encoding zinc finger protein of the cerebellum 5, a related family member on chromosome 13.
Synonyms
HPE 5; HPE5; Odd paired homolog Drosophila; Zic 2; Zic family member 2 odd paired Drosophila homolog; Zic family member 2; ZIC2; ZIC2_HUMAN; Zinc finger protein of the cerebellum 2; Zinc finger protein ZIC 2; Zinc finger protein Zic2.
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Cross Reactivity
Rat
Immunogen
201-300/532
Target
Zic2
Clonality
Polyclonal
Isotype
IgG
Conjugation
APC-Cy7
Source
KLH conjugated synthetic peptide derived from human Zic2
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
650nm/780nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Predicted Cross Reactivity
Human, Mouse, Cow, Sheep, Pig, Chicken
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