RAPGEF2 Polyclonal Antibody, AbBy Fluor™ 350 Conjugated
Product Specifications
Background
PDZ-GEF1 is a 1,499 amino acid cell membrane protein that functions as a guanine nucleotide exchange factor for Rap 1A, Rap 1B and Rap 2B GTPases. Expressed at highest levels in brain, PDZ-GEF1 is found at low levels in placenta, heart, lung and kidney, and undergoes post-translational phosphorylation following DNA damage. PDZ-GEF1 interacts with MAGI-2 and contains one Ras-GEF domain, a Ras-associating domain, one PDZ (DHR) domain, a single N-terminal Ras-GEF domain and a cyclic nucleotide-binding domain. The gene encoding PDZ-GEF1 maps to human chromosome 4q32.1.
Synonyms
KIAA0313; Neural RAP guanine nucleotide exchange protein; nRap GEP; NRAPGEP; PDZ domain containing guanine nucleotide exchange factor 1; PDZ domain-containing guanine nucleotide exchange factor 1; PDZ GEF1; PDZ-GEF1; PDZGEF1; RA GEF; RA-GEF; Rap guanine nucleotide exchange factor 2; Rapgef2; RPGF2_HUMAN.
Cellular Locus
Cytoplasm, Cell membrane
Host
Rabbit
Immunogen
501-600/1499
Target
RAPGEF2
Clonality
Polyclonal
Isotype
IgG
Conjugation
AbBy Fluor™ 350
Source
KLH conjugated synthetic peptide derived from human RAPGEF2
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
346nm/442nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Predicted Cross Reactivity
Human, Mouse, Rat, Dog, Cow, Sheep, Pig, Chicken, Rabbit
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
