NPY5R Polyclonal Antibody

Pancreatic polypeptide (PP), neuropeptide Y (NPY), and peptide YY (PYY) are related 36-amino acid hormones. A number of structurally related receptors for these peptides have been isolated, NPY1-R, NPY2-R, NPY3-R, NPY4-R, NPY5-R, and NPY6-R. NPY4-R is expressed in several human tissues, including brain, coronary artery, and ileum. NPY4-R maps to human chromosome 10q11.2. NPY-5R, isolated from rat hypothalamus, encodes a 456-amino acid protein with less than 35% overall identity to known Y-type receptors. The human NPY5-R sequence is nearly identical to, but in the opposite orientation from, that of the human NPY1-R sequence. NPY5-R localizes to the paraventricular hypothalamic nucleus, the lateral hypothalamus, and other locations consistent with a role in the control of feeding behavior. The gene which encodes NPY5-R maps to human chromosome 4q32.2. NPY6-R is abundantly expressed in human heart and skeletal muscle and the gene which encodes NPY6-R maps to human chromosome 5q31.

Neuropeptide Y receptor type 5; Neuropeptide Y receptor Y5; NPY 5R; NPY R5; NPY Y5; NPY Y5 receptor; NPY-Y5 receptor; NPY5 R; NPY5-R; NPY5R; NPY5R_HUMAN; NPYR 5; NPYR5; NPYY 5; NPYY5; NPYY5-R; Y5 receptor.