EDG8 Polyclonal Antibody, RBITC Conjugated
Product Specifications
Background
Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P) . S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G (i/0) alpha and G (12) subclass of heteromeric G-proteins (By similarity) . May play a regulatory role in the transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells.
Synonyms
EDG8; S1P5; Edg-8; SPPR-1; SPPR-2; Sphingosine 1-phosphate receptor 5; S1P receptor 5; Endothelial differentiation G-protein-coupled receptor 8; Sphingosine 1-phosphate receptor Edg-8; S1P receptor Edg-8; S1PR5
Gene ID
53637
Swiss Prot
Q9H228
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Mouse
Immunogen
1-200/398
Target
EDG8
Clonality
Polyclonal
Isotype
IgG
Conjugation
RBITC
Source
KLH conjugated synthetic peptide derived from human EDG8
Applications
IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
570nm/595nm
Concentration
1µg/µl
Dilution
IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
53637
Predicted Cross Reactivity
Human, Rat, Sheep, Pig, Horse, Rabbit
Curated Selection
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