Sauvagin Polyclonal Antibody
Product Specifications
Background
Sauvagine is a 40-residue peptide isolated and characterized from frog skin. It shares significant structural homology with and elicits similar biological responses as corticotropin-releasing factor (CRF) . It has high affinity for both the CRF1 and CRF2 receptors (and low affinity for the CRF binding protein), suggesting its potential as a pharmacological tool for the study of these receptor sub-types. Due to the binding to CRF2 receptors and their role in the release of ACTH and beta-endorphin during stress, possible areas of research with this ligand include anxiety, depression and obesity.
Synonyms
Sauvagin; Sauvagine; SVG; SAUV_PHYSA.
Cellular Locus
Secreted
Host
Rabbit
Cross Reactivity
Xenopus laevis
Immunogen
1-40/40
Target
Sauvagin
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from frog Sauvagine (C-QGPPISIDLSLELLRKMIEIEKQEKEKQQAANNRLLLDTI-NH2)
Applications
ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Cross Reactivity Details
Xenopus laevis
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