GIOT1 Polyclonal Antibody, AbBy Fluor™ 488 Conjugated
Product Specifications
Background
GIOT-1 is a 563 amino acid protein belonging to the Kr_ppel C2H2-type zinc-finger protein family. Localized to the nucleus, GIOT-1 is widely expressed in tissues, with highest levels in liver, kidney, small intestine, pancreas and thymus. GIOT-1 contains 12 C2H2-type zinc fincers and one KRAB domain. Because the KRAB domain functions as a transcriptional repressor when attached to the template DNA, GIOT-1 is thought to be involved in transcriptional regulation. The gene encoding GIOT-1 is localized to chromosome 19q13.12 and two isoforms of GIOT-1 exist as a result of alternative splicing events.
Synonyms
GIOT-1; GIOT 1; Gonadotropin inducible ovary transcription repressor 1; Gonadotropin inducible transcription repressor 1; Gonadotropin-inducible ovary transcription repressor 1; Zinc finger protein 461; ZN461_HUMAN; ZNF461.
Gene ID
92283
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Mouse
Immunogen
191-240/563
Target
GIOT1
Clonality
Polyclonal
Isotype
IgG
Conjugation
AbBy Fluor™ 488
Source
KLH conjugated synthetic peptide derived from human GIOT1/ZNF461 (191-240aa)
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
499nm/519nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
92283
Predicted Cross Reactivity
Human
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC680257-100 1x 100 µL
Cytokeratin, HMW (AE-3), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC400630-500 1x 500 µL
Mucin 1 / EMA / Episialin / CD227 (VU-2G7), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC402221-500 1x 500 µL
Bcl-2 (Apoptosis & Follicular Lymphoma Marker) (rBCL2/782), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details