CLSTN2 Polyclonal Antibody, Cy5.5 Conjugated
Product Specifications
Background
Members of the calsyntenin protein family are localized to the post-synaptic membrane of exicitatory central nervous system (CNS) synapses. Calsyntenin-2, also known as Alcadein-gamma, is a 955 amino acid protein that localizes to the endoplasmic reticulum, golgi apparatus and plasma membranes. Containing 2 cadherin-like repeats in its N-terminal extracellular region, calsyntenin-2 binds synaptic calcium with its cytoplasmic domain, suggesting a role in the modulation of calcium-mediated postsynaptic signals. Under normal physiological conditions, calsyntenin-2 is protoeolytically processed in an event in which the primary zeta-cleavage generates a short C-terminal transmembrane fragment and a long extracellular N-terminal domain.
Synonyms
Alc; Alcadein; Alcadein Gamma; Alcagamma; Alzheimer's disease related cadherin like protein; Calsyntenin 2; CLSTN 2; CS 2; CS2; FLJ39113; FLJ39499; MGC119560; CSTN2_HUMAN.
Cellular Locus
Cytoplasm, Cell membrane
Host
Rabbit
Cross Reactivity
Mouse
Immunogen
261-360/955
Target
CLSTN2
Clonality
Polyclonal
Isotype
IgG
Conjugation
Cy5.5
Source
KLH conjugated synthetic peptide derived from human CLSTN2
Applications
IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
675nm/694nm
Concentration
1µg/µl
Dilution
IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Predicted Cross Reactivity
Human, Rat, Cow, Pig, Horse, Chicken, Rabbit
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