CLSTN2 Polyclonal Antibody, Biotin Conjugated
Product Specifications
Background
Members of the calsyntenin protein family are localized to the post-synaptic membrane of exicitatory central nervous system (CNS) synapses. Calsyntenin-2, also known as Alcadein-gamma, is a 955 amino acid protein that localizes to the endoplasmic reticulum, golgi apparatus and plasma membranes. Containing 2 cadherin-like repeats in its N-terminal extracellular region, calsyntenin-2 binds synaptic calcium with its cytoplasmic domain, suggesting a role in the modulation of calcium-mediated postsynaptic signals. Under normal physiological conditions, calsyntenin-2 is protoeolytically processed in an event in which the primary zeta-cleavage generates a short C-terminal transmembrane fragment and a long extracellular N-terminal domain.
Synonyms
Alc; Alcadein; Alcadein Gamma; Alcagamma; Alzheimer's disease related cadherin like protein; Calsyntenin 2; CLSTN 2; CS 2; CS2; FLJ39113; FLJ39499; MGC119560; CSTN2_HUMAN.
Cellular Locus
Cytoplasm, Cell membrane
Host
Rabbit
Cross Reactivity
Mouse
Immunogen
261-360/955
Target
CLSTN2
Clonality
Polyclonal
Isotype
IgG
Conjugation
Biotin
Source
KLH conjugated synthetic peptide derived from human CLSTN2
Applications
ELISA, IHC-P, IHC-F
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Predicted Cross Reactivity
Human, Rat, Cow, Pig, Horse, Chicken, Rabbit
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
RDR-NR3C1-Hu-01 96 Tests
Human Nuclear Receptor Subfamily 3, Group C, Member 1 (NR3C1) ELISA Kit
Ask
View Details RDR-NR3C1-Hu-02 48 Tests
Human Nuclear Receptor Subfamily 3, Group C, Member 1 (NR3C1) ELISA Kit
Ask
View Details 