Lymphotactin Polyclonal Antibody, RBITC Conjugated
Product Specifications
Background
Lymphotactin is a chemokine-like molecule produced selectively, if not exclusively, by activated CD8+ T cells (1) . Lymphotactin is a C-type member of the chemokine superfamily, but retains only the 2nd and 4th of the four cysteine residues conserved in other chemokines (3,4) . In normal tissues, lymphotactin is expressed at high levels in spleen, thymus, small intestine, and peripheral blood leukocytes, as well as at low levels in lung, prostate, and ovary (2) . Lymphotactin is chemotactic for CD4+ and CD8+ T cells but not for monocytes, and induces a rise in intracellular calcium in peripheral blood lymphocytes (1) . The specific receptor for lymphotactin is XCR1, a member of the G protein-coupled receptor family (5) . The gene which encodes lymphotactin maps to human chromosome 1q23 (1,2) .
Synonyms
Lptn; LTN; XCL1 C mot chemokine 1; SCM 1 alpha; ATAC; Chemokine C Mot Ligand 1; Cytokine SCM-1; LPTN; LTN; Lymphotactin; Lymphotaxin; SCM-1-alpha; SCM1; SCYC1; Small inducible cytokine C1; Small Inducible Cytokine Subfamily C Member 1; Small-inducible cytokine C1; XC chemokine ligand 1; Xcl1; XCL1_HUMAN.
Cellular Locus
Secreted
Host
Rabbit
Immunogen
21-114/114
Target
Lymphotactin
Clonality
Polyclonal
Isotype
IgG
Conjugation
RBITC
Source
KLH conjugated synthetic peptide derived from human Lymphotactin
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
570nm/595nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Predicted Cross Reactivity
Human
Curated Selection
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