Lymphotactin Polyclonal Antibody

Lymphotactin is a chemokine-like molecule produced selectively, if not exclusively, by activated CD8+ T cells (1) . Lymphotactin is a C-type member of the chemokine superfamily, but retains only the 2nd and 4th of the four cysteine residues conserved in other chemokines (3,4) . In normal tissues, lymphotactin is expressed at high levels in spleen, thymus, small intestine, and peripheral blood leukocytes, as well as at low levels in lung, prostate, and ovary (2) . Lymphotactin is chemotactic for CD4+ and CD8+ T cells but not for monocytes, and induces a rise in intracellular calcium in peripheral blood lymphocytes (1) . The specific receptor for lymphotactin is XCR1, a member of the G protein-coupled receptor family (5) . The gene which encodes lymphotactin maps to human chromosome 1q23 (1,2) .

Lptn; LTN; XCL1 C mot chemokine 1; SCM 1 alpha; ATAC; Chemokine C Mot Ligand 1; Cytokine SCM-1; LPTN; LTN; Lymphotactin; Lymphotaxin; SCM-1-alpha; SCM1; SCYC1; Small inducible cytokine C1; Small Inducible Cytokine Subfamily C Member 1; Small-inducible cytokine C1; XC chemokine ligand 1; Xcl1; XCL1_HUMAN.