SOX12 Polyclonal Antibody, AbBy Fluor™ 488 Conjugated
Product Specifications
Background
Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.
Synonyms
Homo sapiens SRY sex determining region Y box 12; Protein SOX-22; SOX 12; SOX 12 protein; SOX 22; SOX 22 protein; sox12; SOX12 protein; SOX12_HUMAN; SOX22 protein; SRY sex determining region Y box 12; SRY sex determining region Y box 22; SRY box 12; SRY box 22; SRY related HMG box gene 22; Transcription factor Sox-12.
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Human
Immunogen
51-150/315
Target
SOX12
Clonality
Polyclonal
Isotype
IgG
Conjugation
AbBy Fluor™ 488
Source
KLH conjugated synthetic peptide derived from human SOX22
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
499nm/519nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Predicted Cross Reactivity
Mouse, Rat, Cow
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
