PAX6 Polyclonal Antibody, AbBy Fluor™ 555 Conjugated
Product Specifications
Background
Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells (By similarity) . Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity) . Isoform 5a appears to function as a molecular switch that specifies target genes.
Synonyms
AN; AN2; FVH1; MGDA; WAGR; D11S812E; Paired box protein Pax-6; Aniridia type II protein; Oculorhombin; PAX6
Gene ID
5080
Swiss Prot
P26367
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Immunogen
51-150/422
Target
PAX6
Clonality
Polyclonal
Isotype
IgG
Conjugation
AbBy Fluor™ 555
Source
KLH conjugated synthetic peptide derived from human PAX6
Applications
FCM, IF (IHC-P), IF (IHC-F)
Purification
Purified by Protein A.
Excitation Emission
553nm/568nm
Concentration
1µg/µl
Dilution
FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Specificity
Belongs to the paired homeobox family.
Gene ID URL
5080
Predicted Cross Reactivity
Dog, Cow, Sheep, Horse, Chicken, Rabbit
Curated Selection
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