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PAX6 Polyclonal Antibody, APC Conjugated

Product Specifications

Background

Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells (By similarity) . Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity) . Isoform 5a appears to function as a molecular switch that specifies target genes.

Synonyms

AN; AN2; FVH1; MGDA; WAGR; D11S812E; Paired box protein Pax-6; Aniridia type II protein; Oculorhombin; PAX6

Gene ID

5080

Swiss Prot

P26367

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Immunogen

51-150/422

Target

PAX6

Clonality

Polyclonal

Isotype

IgG

Conjugation

APC

Source

KLH conjugated synthetic peptide derived from human PAX6

Applications

FCM, IF (IHC-P), IF (IHC-F)

Purification

Purified by Protein A.

Excitation Emission

650nm/660nm

Concentration

1µg/µl

Dilution

FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Specificity

Belongs to the paired homeobox family.

Gene ID URL

5080

Predicted Cross Reactivity

Dog, Cow, Sheep, Horse, Chicken, Rabbit

Curated Selection

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