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IQGAP1 Polyclonal Antibody, AbBy Fluor™ 488 Conjugated

Product Specifications

Background

Binds to activated CDC42 but does not stimulate its GTPase activity. It associates with calmodulin. Could serve as an assembly scaffold for the organization of a multimolecular complex that would interface incoming signals to the reorganization of the actin cytoskeleton at the plasma membrane. May promote neurite outgrowth.

Synonyms

SAR1; p195; HUMORFA1; Ras GTPase-activating-like protein IQGAP1; IQGAP1; KIAA51

Gene ID

8826

Swiss Prot

P46940

Cellular Locus

Nucleus, Cell membrane

Host

Rabbit

Cross Reactivity

Human, Rat, Rabbit

Immunogen

1451-1550/1657

Target

IQGAP1

Clonality

Polyclonal

Isotype

IgG

Conjugation

AbBy Fluor™ 488

Source

KLH conjugated synthetic peptide derived from human IQGAP1

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

499nm/519nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

8826

Predicted Cross Reactivity

Mouse

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