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IQGAP1 Polyclonal Antibody, APC Conjugated

Product Specifications

Background

Binds to activated CDC42 but does not stimulate its GTPase activity. It associates with calmodulin. Could serve as an assembly scaffold for the organization of a multimolecular complex that would interface incoming signals to the reorganization of the actin cytoskeleton at the plasma membrane. May promote neurite outgrowth.

Synonyms

SAR1; p195; HUMORFA1; Ras GTPase-activating-like protein IQGAP1; IQGAP1; KIAA51

Gene ID

8826

Swiss Prot

P46940

Cellular Locus

Nucleus, Cell membrane

Host

Rabbit

Cross Reactivity

Human, Rat, Rabbit

Immunogen

1451-1550/1657

Target

IQGAP1

Clonality

Polyclonal

Isotype

IgG

Conjugation

APC

Source

KLH conjugated synthetic peptide derived from human IQGAP1

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

650nm/660nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

8826

Predicted Cross Reactivity

Mouse

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