NIPAL2 Polyclonal Antibody, AbBy Fluor™ 647 Conjugated
Product Specifications
Background
Non-imprinted in Prader-Willi/Angelman syndrome (NIPA) proteins are highly conserved receptors or transporters. A family known as the NIPA-like domain containing (NPAL) proteins are closely related to the NIPA proteins, but most are uncharacterized and their functions are unknown. NPAL2 (NIPA-like domain containing 2), also known as NIPAL2, is a 368 amino acid multi-pass membrane protein belonging to the NIPA family and is encoded by a gene located on human chromosome 8. Human chromosome 8 consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that map to chromosome 8.
Synonyms
NIPA like domain containing 2; NIPAL2; NPAL2; NPAL2_HUMAN.
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Mouse
Immunogen
1-100/368
Target
NIPAL2
Clonality
Polyclonal
Isotype
IgG
Conjugation
AbBy Fluor™ 647
Source
KLH conjugated synthetic peptide derived from human NIPAL2
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
650nm/665nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Predicted Cross Reactivity
Human, Rat, Cow, Sheep, Pig, Horse, Rabbit
Curated Selection
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