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Procollagen type IIA Polyclonal Antibody, Biotin Conjugated

Product Specifications

Background

Collagen type II is the most abundant protein of cartilage matrix. Two isoforms exist and collagen type IIA is involved in early development of cartilage in embryos. The collagen is produced from type II procollagen when two teloterminal propeptides are digested from the precursor and released into the circulation. Procollagen type II N-terminal propeptide is considered a marker of cartilage synthesis and the normal concentration in serum is approximately 30ng/mL.

Synonyms

Collagen II N-terminal propeptide; Collagen II alpha 1; COL2A1; COL2A1 protein; collagen, type II, alpha 1; collagen alpha-1II; type II collagen; alpha-1 type II collagen; alpha1 type II collagen; Col2a1; AOM; Cartilage collagen; COL11A3; Collagen alpha 1II chain precursor; Collagen II alpha 1 polypeptide; Collagen type II alpha 1 primary osteoarthritis spondyloepiphyseal dysplasia congenital; MGC131516; SEDC; Collagen alpha-1II chain; Alpha-1 type II collagen; CO2A1_HUMAN.

Cellular Locus

Secreted, Extracellular matrix

Host

Rabbit

Cross Reactivity

Zebrafish

Immunogen

1-100/1487

Target

Procollagen type IIA

Clonality

Polyclonal

Isotype

IgG

Conjugation

Biotin

Source

KLH conjugated synthetic peptide derived from human Collagen II alpha 1

Applications

ELISA, IHC-P, IHC-F

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C for 12 months.

Predicted Cross Reactivity

Human, Dog, Cow, Sheep, Pig, Chicken, Rabbit, Guinea Pig

Frequently Asked Questions

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